Guardian 4 is factory calibrated at manufacture and requires zero fingerstick confirmations during the 7-day wear period, reducing the calibration burden that limited adoption of earlier CGM generations. The 780G pump’s SmartGuard algorithm automatically adjusts basal insulin and delivers correction boluses every 5 minutes based on Guardian 4 readings, achieving an average of 78% time in range in clinical trials. Predictive alerts warn of hypoglycaemia 20 minutes before the projected low, with automatic insulin suspension before the event. The sensor transmits directly to the pump’s dedicated radio and simultaneously to the MiniMed Mobile app for remote monitoring. Compatible with CareLink personal and professional platforms for quarterly endocrinology review.